Description

Guanosine 2',3'-Cyclic Phosphate Triethylamine Salt is a chemically modified nucleotide derivative where the triethylamine acts as a counterion for the phosphate group. This compound is a crucial biochemical reagent and synthetic intermediate, valued for its role in studying RNA structure, metabolism, and enzyme mechanisms. It is primarily utilized by research institutions, pharmaceutical developers, and biotechnology companies engaged in nucleotide chemistry, molecular biology, and the development of nucleic acid-based therapeutics.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for ribonucleases and phosphodiesterases involved in RNA turnover.
• Nucleotide Chemistry: Serves as a key synthetic intermediate or building block for the preparation of modified nucleosides, nucleotides, and oligonucleotides.
• Pharmaceutical Development: Employed in the research and development of antiviral agents, mRNA-based vaccines, and other therapeutic nucleic acids.
• Diagnostic Reagent Manufacturing: A potential component in the formulation of kits for molecular diagnostics and research assays.
• Enzyme Mechanism Studies: Acts as a model compound to investigate the catalytic mechanisms of enzymes that process cyclic phosphate intermediates in RNA.

Basic Information

Item	Details
Product Name	Guanosine 2',3'-Cyclic Phosphate Triethylamine Salt
CAS No.	73647-09-3
Molecular Formula	C16H29N6O7P
Molecular Weight	448.42 g/mol
Synonyms	2',3'-cGMP Triethylamine Salt; Guanosine 2',3'-cyclic monophosphate TEA salt; 2',3'-Cyclic GMP triethylammonium salt; 9-β-D-Ribofuranosylguanine 2',3'-(hydrogen phosphate) triethylamine salt; G>p triethylamine salt; cGMP (2',3') TEA salt
EINECS	Contact for details

Quality Control

Our Guanosine 2',3'-Cyclic Phosphate Triethylamine Salt is produced under a rigorous quality management system. Each batch is subjected to comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. Certificates of Analysis (COA) documenting all specifications are available upon request to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.