Description

2-[[(4-Methoxy-3,5-Dimethyl-2-Pyridinyl)Methyl]Sulfinyl]-1H-Benzimidazole is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) of significant commercial importance. Its primary value lies in its role as the key chemical entity in the synthesis of proton pump inhibitors, a major class of therapeutics. This compound is essential for manufacturers in the pharmaceutical and fine chemical industries focused on producing gastrointestinal medications.

Application

• Active Pharmaceutical Ingredient (API) for the synthesis of advanced proton pump inhibitor drugs.
• Pharmaceutical Intermediate in the large-scale commercial production of gastrointestinal therapeutics.
• Reference Standard for quality control and analytical method development in pharmaceutical R&D and manufacturing.
• Chemical Synthesis Building Block for research into novel benzimidazole derivatives with potential biological activity.
• Process Development for optimizing manufacturing routes and scaling up production of related active compounds.

Basic Information

Product Name	2-[[(4-Methoxy-3,5-Dimethyl-2-Pyridinyl)Methyl]Sulfinyl]-1H-Benzimidazole
CAS No.	73590-60-0
Molecular Formula	C16H17N3O2S
Molecular Weight	315.39 g/mol
Synonyms	Omeprazole Sulfide; Omeprazole Impurity C; 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazole; H 168/22; 5-Methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methylthio]-1H-benzimidazole; Timoprazole; Picoprazole; AG-1749
EINECS	Contact for details

Quality Control

Our production of this pharmaceutical intermediate adheres to stringent GMP guidelines to ensure batch-to-batch consistency and traceability. Quality is verified through a comprehensive suite of analytical tests including HPLC for purity and related substances, IR and NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.