Description

Pregn-4-Ene-3,20-Dione Hydrochloride is a high-purity steroid derivative, specifically the hydrochloride salt of progesterone, valued for its enhanced stability and solubility profile in research and development applications. This compound is critical for pharmaceutical and biochemical research, serving as a key intermediate or reference standard in the synthesis and analysis of steroid-based therapeutics. It is primarily utilized by R&D laboratories, pharmaceutical manufacturers, and academic institutions focused on endocrinology, drug discovery, and analytical method development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Used for method development, validation, and quality control testing in HPLC, GC, and other chromatographic systems.
• Biochemical Research: Employed in studies investigating progesterone receptor interactions, hormonal pathways, and metabolic processes.
• Veterinary Medicine: Potential use in the development of hormonal treatments and fertility management for animals.
• Academic & Contract Research: Serves as a reagent for university laboratories and CROs (Contract Research Organizations) conducting fundamental and applied life science research.

Basic Information

Product Name	Pregn-4-Ene-3,20-Dione Hydrochloride
CAS No.	73489-90-4
Molecular Formula	C21H31ClO2
Molecular Weight	350.93 g/mol
Synonyms	Progesterone Hydrochloride; 4-Pregnene-3,20-dione Hydrochloride; 3,20-Dioxopregn-4-ene Hydrochloride; NSC 9704 Hydrochloride; Pregn-4-ene-3,20-dione, hydrochloride; 20-Oxopregn-4-en-3-one Hydrochloride
EINECS	Contact for details

Quality Control

Our Pregn-4-Ene-3,20-Dione Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications suitable for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.