Description

3-Methoxy-2, 3-Dihydrowithaferin-A is a specialized withanolide derivative, a class of bioactive compounds primarily found in plants of the Solanaceae family. This compound is valued for its role as a key intermediate and reference standard in advanced pharmaceutical and phytochemical research. It is essential for researchers and manufacturers in the pharmaceutical, nutraceutical, and academic sectors who are developing or studying novel therapeutic agents derived from natural products.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis and structural modification of novel withanolide-based drug candidates.
• Reference Standard: Used as a high-purity analytical standard for the identification and quantification of withanolides in complex botanical extracts via HPLC, LC-MS, or NMR.
• Bioactivity Studies: Employed in in-vitro and in-vivo studies to investigate its pharmacological properties, such as anti-inflammatory, anti-cancer, or immunomodulatory effects.
• Natural Product Chemistry: A key compound for studying the structure-activity relationships (SAR) within the withanolide family to guide the development of more potent analogs.
• Nutraceutical Standardization: Used to standardize and authenticate herbal formulations containing Withania somnifera (Ashwagandha) or related species for consistent potency.

Basic Information

Product Name	3-Methoxy-2, 3-Dihydrowithaferin-A
CAS No.	73365-94-3
Molecular Formula	C29H38O7
Molecular Weight	498.61 g/mol
Synonyms	3-Methoxy-2,3-dihydro-withaferin A; 2,3-Dihydro-3-methoxywithaferin A; 3-Methoxy-2,3-dihydro-27-deoxywithaferin A; Withanolide derivative; 3-Methoxy-2,3-dihydro-27-deoxy-14,15-dihydroxywithaferin A; (22R)-3β-Methoxy-5α,6β,14α,15β,17β,20β-hexahydroxy-1-oxoergosta-2,24-dien-26-oic acid δ-lactone; 3-Methoxy-2,3-dihydro-27-deoxy-14,15-dihydroxywithaferin A
EINECS	Contact for details

Quality Control

Our 3-Methoxy-2, 3-Dihydrowithaferin-A is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term stability, storage at 2-8°C is recommended. The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.