Description

3β-[(β-D-Glucopyranosyl)Oxy]-14-Hydroxy-19-Oxobufa-4,20,22-Trienolide is a specialized cardiac glycoside derivative, a class of compounds known for their potent biological activity. This high-purity reference standard is critical for pharmaceutical research and development, particularly in the study of cardiotonic agents and natural product chemistry. It is primarily utilized by research institutions, pharmaceutical companies, and analytical laboratories for method development, quality control, and biological screening.

Application

• Pharmaceutical Reference Standard: Serves as a certified primary standard for the identification, assay, and impurity profiling of related cardiac glycosides in drug substances and products.
• Biochemical Research: Used as a key reagent in pharmacological studies to investigate mechanisms of action related to sodium-potassium ATPase inhibition and cardiac contractility.
• Natural Product Isolation & Analysis: Acts as a critical marker compound for the isolation, characterization, and standardization of extracts from Bufo toad venom and related botanical sources.
• Analytical Method Development: Employed in developing and validating HPLC, LC-MS, and other chromatographic methods for the precise quantification of complex natural products.
• Impurity Standard: Used to qualify and control related substances in the manufacturing of sophisticated active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3β-[(β-D-Glucopyranosyl)Oxy]-14-Hydroxy-19-Oxobufa-4,20,22-Trienolide
CAS No.	73309-75-8
Molecular Formula	C30H42O10
Molecular Weight	562.65 g/mol
Synonyms	19-Oxobufalin 3-O-β-D-glucopyranoside; Bufalin 3-O-β-D-glucoside, 19-oxo-; 19-Oxobufalin glucoside; 3β-(β-D-Glucopyranosyloxy)-14-hydroxy-19-oxobufa-4,20,22-trienolide; 14-Hydroxy-19-oxobufa-4,20,22-trienolide 3-β-D-glucopyranoside; Telocinobufagin 3-O-β-D-glucopyranoside (related); A Bufadienolide glycoside
EINECS	Contact for details

Quality Control

Every batch of 3β-[(β-D-Glucopyranosyl)Oxy]-14-Hydroxy-19-Oxobufa-4,20,22-Trienolide is manufactured and analyzed under strict quality management systems. Our products undergo rigorous identity, purity, and strength testing using advanced analytical techniques including HPLC, LC-MS, and NMR to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.