Description

1-Pyrrolidinecarbonyl Chloride, 2,4-Dimethyl-, cis- (9Ci) is a specialized organic intermediate featuring a reactive acid chloride group on a substituted pyrrolidine scaffold. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by fine chemical manufacturers and R&D laboratories engaged in creating novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, particularly those containing pyrrolidine-based pharmacophores.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where its specific stereochemistry is leveraged.
• Peptidomimetic Research: Serves as a building block for creating peptide analogs and protease inhibitors in medicinal chemistry.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Utilized in the development of novel polymers and functional materials with tailored properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	1-Pyrrolidinecarbonyl Chloride, 2,4-Dimethyl-, cis- (9Ci)
CAS No.	73291-04-0
Molecular Formula	C7H12ClNO
Molecular Weight	161.63 g/mol
Synonyms	cis-2,4-Dimethylpyrrolidine-1-carbonyl chloride; (2S,4S)-2,4-Dimethylpyrrolidine-1-carbonyl chloride; 2,4-Dimethyl-1-pyrrolidinecarbonyl chloride, cis-; 1-Carbamoyl-2,4-dimethylpyrrolidine chloride; Pyrrolidine-1-carbonyl chloride, 2,4-dimethyl-, cis-
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarbonyl Chloride, 2,4-Dimethyl-, cis- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopic methods, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ISO 9001 standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Chiral Purity (Chiral HPLC)	≥ 98.0% cis-isomer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.