Description

Lamtidine CAS NO 73278-54-3 is a high-purity pharmaceutical intermediate and active ingredient belonging to the histamine H2-receptor antagonist class. It is a critical component in the research and development of therapeutic agents targeting gastric acid secretion. This compound is essential for pharmaceutical manufacturers and research institutions focused on gastroenterology and metabolic disorders. We supply it with a commitment to stringent quality control and reliable global logistics.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of anti-ulcer and gastroesophageal reflux disease (GERD) medications.
• Research & Development: Key intermediate in the synthesis of novel H2-antagonist drug candidates and for pharmacological studies.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development and quality control testing.
• Chemical Synthesis: Serves as a building block for the preparation of more complex molecules in medicinal chemistry.

Basic Information

Product Name	Lamtidine
CAS No.	73278-54-3
Molecular Formula	C22H28N4O4S
Molecular Weight	452.55 g/mol
Synonyms	Lamtidine; SK&F 93479; 2-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(2-[[(diaminomethylene)amino]oxy]ethyl)acetamide; 2-({[2-(Carbamimidamido)-1,3-thiazol-4-yl]methyl}sulfanyl)-N-(2-{[(diaminomethylidene)amino]oxy}ethyl)acetamide; SKF-93479; SKF 93479
EINECS	Contact for details

Quality Control

Our Lamtidine is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can support compliance with cGMP, ICH Q7 guidelines, and relevant pharmacopoeial standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.