Description

Bicyclo[2.2.2]Oct-5-Ene-2-Carbonyl Chloride, 3-Methyl-, (1Alpha,2Beta,3Alpha,4Alpha)- (9Ci) is a highly functionalized bicyclic acid chloride derivative, serving as a critical chiral building block in advanced organic synthesis. Its rigid, three-dimensional structure and reactive carbonyl chloride group make it invaluable for constructing complex molecular architectures with precise stereochemistry. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of new drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides with specific stereochemical requirements for enhanced activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Building block for specialty polymers and advanced organic materials with unique structural properties.
• Academic & Industrial R&D: Essential reagent for methodological studies in organic chemistry and process development.

Basic Information

Product Name	Bicyclo[2.2.2]Oct-5-Ene-2-Carbonyl Chloride, 3-Methyl-, (1Alpha,2Beta,3Alpha,4Alpha)- (9Ci)
CAS No.	73208-90-9
Molecular Formula	C10H11ClO
Molecular Weight	182.65 g/mol
Synonyms	3-Methylbicyclo[2.2.2]oct-5-ene-2-carbonyl chloride; (1α,2β,3α,4α)-3-Methylbicyclo[2.2.2]oct-5-ene-2-carbonyl chloride; 3-Methyl-5-norbornene-2-carbonyl chloride (stereospecific); Bicyclo[2.2.2]oct-5-ene-2-carbonyl chloride, 3-methyl-, (1α,2β,3α,4α)-; 73208-90-9; 3-Methylbicyclo[2.2.2]oct-5-en-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.2]Oct-5-Ene-2-Carbonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, critical for sensitive synthetic applications. All materials undergo comprehensive analysis including HPLC for purity and chiral methods to confirm stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.