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1,2,3,4-Tetra-o-Acetyl-6-Azido-6-Deoxy-α-D-Galactopyranose CAS NO 73108-24-4
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CAS No.:73108-24-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1,2,3,4-Tetra-o-Acetyl-6-Azido-6-Deoxy-α-D-Galactopyranose is a key protected monosaccharide derivative, specifically a 6-azido galactose building block with acetyl protecting groups. This compound is essential for synthetic chemists as it provides a versatile, reactive azido handle for further functionalization via click chemistry, such as the copper-catalyzed azide-alkyne cycloaddition (CuAAC). It is primarily used by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the synthesis of complex glycoconjugates, glycomimetics, and carbohydrate-based drug candidates.
Application
- Glycoconjugate Synthesis: A critical intermediate for constructing complex oligosaccharides, glycopeptides, and glycolipids used in drug discovery and biological studies.
- Click Chemistry Substrate: The 6-azido group enables efficient, high-yield conjugation with alkynes, making it ideal for bioconjugation, labeling, and polymer modification.
- Carbohydrate-Based Drug Development: Serves as a building block for creating novel glycomimetics and therapeutic agents targeting lectins, enzymes, and other biological receptors.
- Chemical Biology Probes: Used to synthesize activity-based probes and diagnostic tools for studying glycosylation processes and carbohydrate-protein interactions.
- Material Science: Employed in the surface functionalization of biomaterials and nanoparticles to introduce bioactive carbohydrate motifs.
- Academic & Industrial Research: A fundamental reagent for methodological development in synthetic organic chemistry and glycoscience.
Basic Information
| Product Name | 1,2,3,4-Tetra-o-Acetyl-6-Azido-6-Deoxy-α-D-Galactopyranose |
| CAS No. | 73108-24-4 |
| Molecular Formula | C14H19N3O9 |
| Molecular Weight | 373.32 g/mol |
| Synonyms | 6-Azido-6-deoxy-1,2,3,4-tetra-O-acetyl-α-D-galactopyranose; 6-Azido-1,2,3,4-tetra-O-acetyl-α-D-galactopyranose; 1,2,3,4-Tetra-O-acetyl-6-azido-6-deoxy-α-D-galactopyranose; α-D-Galactopyranose, 6-azido-6-deoxy-, 1,2,3,4-tetraacetate; 6-Azido-6-deoxy-α-D-galactopyranose tetraacetate; Tetra-O-acetyl-6-azido-6-deoxy-α-D-galactose; 6-N3-α-D-Galp(Ac)4; Azido-galactose tetraacetate |
| EINECS | Contact for details |
Quality Control
Our 1,2,3,4-Tetra-o-Acetyl-6-Azido-6-Deoxy-α-D-Galactopyranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency, meeting the stringent requirements for research and process development. Comprehensive Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent decomposition.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Specific Rotation [α]²⁰D | +90° to +110° (c=1 in CHCl₃) |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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