Description

(R)-Econazole CAS NO 73094-39-0 is the single enantiomer of the broad-spectrum antifungal agent econazole. This optically pure compound is critical for research and development in chiral pharmacology, offering a precise tool for studying stereospecific biological activity. It is primarily utilized by pharmaceutical R&D laboratories, academic institutions, and manufacturers of advanced intermediates for enantioselective synthesis.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for analytical method development and quality control of enantiopure antifungal APIs.
• Chiral Intermediate: Used in the enantioselective synthesis of novel antifungal agents and for structure-activity relationship (SAR) studies.
• Biochemical Research: Employed in mechanistic studies to investigate the stereospecific interaction of imidazole antifungals with fungal cytochrome P450 enzymes (lanosterol 14α-demethylase).
• Asymmetric Catalysis Studies: Acts as a chiral ligand precursor or a model substrate in the development of new asymmetric synthetic methodologies.
• Impurity Profiling: Essential for identifying and quantifying the (R)-enantiomer as a potential impurity in batches of racemic econazole or its (S)-enantiomer.

Basic Information

Product Name	(R)-Econazole
CAS No.	73094-39-0
Molecular Formula	C18H15Cl3N2O
Molecular Weight	381.68 g/mol
Synonyms	(R)-Econazole; (R)-1-[2-[(4-Chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole; (R)-Econazole base; (R)-Econazole free base; (+)-Econazole; (R)-(+)-Econazole; (2R)-1-(2,4-Dichloro-β-[(4-chlorobenzyl)oxy]phenethyl)imidazole; UNII-7N6G9P6H4F
EINECS	Contact for details

Quality Control

Our (R)-Econazole is produced under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral HPLC to confirm enantiomeric excess (ee) and standard pharmacopeial identification tests. A Certificate of Analysis (COA) detailing purity, chiral purity, and related substances is provided with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.