Description

(S)-Econazole is the single enantiomer of the broad-spectrum imidazole antifungal agent, offering a high degree of stereochemical purity for advanced pharmaceutical research and development. This specific stereoisomer is of significant interest for studying structure-activity relationships and developing more targeted therapeutic formulations with potentially enhanced efficacy or reduced side-effect profiles. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) focusing on enantiomerically pure antifungal agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel, enantiomerically pure antifungal drugs.
• Biochemical Research: Used as a reference standard and probe in pharmacological studies to investigate the stereoselective interaction of antifungal agents with biological targets.
• Analytical Standard: Employed as a high-purity certified reference material (CRM) for method development and quality control in analytical laboratories.
• API Development: Integral in the research and process development for new antifungal medications requiring a specific enantiomeric form.
• Mechanism of Action Studies: Facilitates research into the precise biological pathways and binding affinities associated with the (S)-enantiomer.

Basic Information

Product Name	(S)-Econazole
CAS No.	73094-37-8
Molecular Formula	C18H15Cl3N2O
Molecular Weight	381.68 g/mol
Synonyms	(S)-1-[2-[(4-Chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole; (S)-Econazole Base; (-)-Econazole; (S)-Econazole Nitrate (salt form); (S)-Econazole free base; (S)-Econazole enantiomer; (2S)-1-(2,4-Dichloro-β-[(4-chlorobenzyl)oxy]phenethyl)imidazole; (S)-Econazole (JP17)
EINECS	Contact for details

Quality Control

Our (S)-Econazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay, to ensure it meets stringent specifications for research and development purposes. A Certificate of Analysis (COA) detailing identity, purity (by HPLC), enantiomeric excess, and related substances is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.