Description

8-Azabicyclo[3.2.1]Octane-2-Carbonyl Chloride, 8-Methyl-, (1R-Exo)- (9Ci) is a high-purity, stereochemically defined bicyclic building block essential for advanced organic synthesis. Its value lies in its role as a versatile acylating agent and key precursor for constructing complex nitrogen-containing molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of tropane alkaloid derivatives and other bioactive molecules with potential therapeutic applications.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides that require a rigid, nitrogen-containing bicyclic scaffold.
• Chemical Research & Development: Serves as a versatile electrophile in academic and industrial R&D for exploring new reaction pathways and creating complex heterocyclic compounds.
• Ligand and Catalyst Precursor: Employed in the preparation of specialized chiral ligands and organocatalysts for asymmetric synthesis.
• Fine Chemical Production: Acts as a key intermediate in the multi-step synthesis of high-value, specialty chemicals for various industrial applications.

Basic Information

Product Name	8-Azabicyclo[3.2.1]Octane-2-Carbonyl Chloride, 8-Methyl-, (1R-Exo)- (9Ci)
CAS No.	73045-47-3
Molecular Formula	C9H12ClNO
Molecular Weight	185.65 g/mol
Synonyms	(1R-exo)-8-Methyl-8-azabicyclo[3.2.1]octane-2-carbonyl chloride; endo-(1R)-8-Methyl-8-azabicyclo[3.2.1]oct-2-ylcarbonyl chloride; 8-Methyl-8-azabicyclo[3.2.1]octane-2-carbonyl chloride, (1R,2R,5S)-rel-; Tropane-2-carbonyl chloride, 8-methyl-, (1R,2R,5S)-; (1R,5S)-8-Methyl-8-azabicyclo[3.2.1]octane-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 8-Azabicyclo[3.2.1]Octane-2-Carbonyl Chloride, 8-Methyl-, (1R-Exo)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.