Description

3β-(D-Glucopyranosyloxy)-5,14-Dihydroxy-19-Oxo-5β-Bufa-20,22-Dienolide is a specialized cardiac glycoside derivative, a compound of significant interest in advanced pharmaceutical research and development. Its core value lies in its potential as a high-purity reference standard or a key synthetic intermediate for novel therapeutic agents. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require precise and reliable building blocks for drug discovery and process development.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control, method validation, and regulatory compliance in the analysis of cardiac glycoside-based drugs.
• Drug Discovery & Development: Serves as a critical intermediate or lead compound in the synthesis and research of new cardiovascular and anticancer therapeutic agents.
• Biochemical Research: Employed in studies investigating the mechanism of action of Na+/K+-ATPase inhibitors and their effects on cellular signaling pathways.
• Academic Research: Utilized in university and institutional laboratories for pharmacological and toxicological studies related to bufadienolides.
• Fine Chemical Synthesis: Acts as a sophisticated starting material or intermediate for the custom synthesis of complex, biologically active molecules.

Basic Information

Product Name	3β-(D-Glucopyranosyloxy)-5,14-Dihydroxy-19-Oxo-5β-Bufa-20,22-Dienolide
CAS No.	72947-90-1
Molecular Formula	C30H42O11
Molecular Weight	578.65 g/mol
Synonyms	19-Oxocinobufagin 3-O-β-D-glucoside; Cinobufagin-3-O-β-D-glucoside; 3-β-Glucosyloxy-5,14-dihydroxy-19-oxo-5β-bufa-20,22-dienolide; 19-Oxocinobufagin glucoside; Bufadienolide glycoside; 3-O-β-D-Glucopyranosylcinobufagin; 5,14-Dihydroxy-19-oxo-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5β-bufa-20,22-dienolide
EINECS	Contact for details

Quality Control

Our 3β-(D-Glucopyranosyloxy)-5,14-Dihydroxy-19-Oxo-5β-Bufa-20,22-Dienolide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.