Description

Neplanocin F is a potent and specific nucleoside analog with significant biological activity. This compound is valued for its role as a key intermediate and research tool in the development of novel antiviral and anticancer therapeutics. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in medicinal chemistry and biochemical research. The high-purity material is essential for ensuring reproducible and reliable experimental results in drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a potent inhibitor of S-adenosylhomocysteine (SAH) hydrolase, making it a valuable tool for studying methylation processes and epigenetic regulation.
• Antiviral Agent Development: Investigated for its activity against a range of viruses due to its mechanism of interfering with viral replication.
• Medicinal Chemistry Studies: Employed in structure-activity relationship (SAR) studies to design and optimize new therapeutic candidates with improved efficacy and safety profiles.
• Enzyme Inhibition Assays: Acts as a reference standard in high-throughput screening and biochemical assays targeting adenosine-metabolizing enzymes.
• Academic Research: Utilized in university and institutional labs for fundamental research in virology, oncology, and cellular signaling pathways.

Basic Information

Product Name	Neplanocin F
CAS No.	72877-51-1
Molecular Formula	C₁₁H₁₃N₅O₃
Molecular Weight	263.25 g/mol
Synonyms	(–)-Neplanocin F; 9-[(1R,2S,3R)-2,3-Dihydroxy-4-(hydroxymethyl)cyclopent-4-en-1-yl]adenine; 3-Deazaneplanocin A analog; Carbocyclic 3-deazaadenosine; c³-Ado; NSC 614373; 3-Deazaneplanocin F
EINECS	Contact for details

Quality Control

Our Neplanocin F is manufactured under strict quality management systems to ensure the highest standards of purity and consistency. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. For long-term storage, consider keeping the container under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.