Description

Neplanocin C is a synthetic carbocyclic nucleoside analog with significant biological activity. This compound is valued for its role as a potent inhibitor of S-adenosylhomocysteine hydrolase (SAH hydrolase), making it a crucial tool in epigenetic and antiviral research. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies engaged in developing novel therapeutics and studying cellular methylation processes.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel antiviral and anticancer agents.
• Epigenetics Studies: Used as a biochemical tool to inhibit SAH hydrolase, thereby modulating cellular methylation pathways for mechanistic research.
• Antiviral Agent Development: Investigated for its potential activity against a range of viruses due to its mechanism of action on nucleotide metabolism.
• Biochemical Assays: Employed as a reference standard or inhibitor in enzymatic assays to study purine metabolism and methyltransferase activity.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in medicinal chemistry and molecular biology.
• Pre-clinical Studies: Acts as a candidate compound for in vitro and in vivo evaluation of pharmacokinetics and pharmacodynamics.

Basic Information

Product Name	Neplanocin C
CAS No.	72877-48-6
Molecular Formula	C₁₁H₁₃N₅O₃
Molecular Weight	263.25 g/mol
Synonyms	(–)-Neplanocin C; Carbocyclic 3-deazaadenosine; 3-Deazaneplanocin C; 4(R),5(S)-Dihydro-5-(6-amino-3-deazapurin-9-yl)-4-(hydroxymethyl)cyclopent-2-en-1-ol; 9-[(1R,2S,3R)-2,3-Dihydroxy-4-methylenecyclopentyl]-3-deazaadenine; 3-Deazaaristeromycin; NSC 377575
EINECS	Contact for details

Quality Control

Every batch of Neplanocin C is manufactured and tested under strict quality management systems to ensure identity, purity, and consistency. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC purity data, confirming compliance with in-house specifications tailored for research and development use. Our quality commitment supports your regulatory and traceability requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.