Description

1(2H)-Pyrimidinecarbonyl Chloride, 3-Ethyltetrahydro-2,4-Dioxo- (9Ci) is a specialized heterocyclic building block featuring a reactive acid chloride group. This compound is a critical intermediate for synthesizing more complex molecules in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, particularly in medicinal chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the pyrimidine core is a common bioactive motif.
• Chemical Research & Development: Serves as a versatile reagent for introducing the 1(2H)-pyrimidinecarbonyl moiety into target molecules via amide or ester bond formation.
• Material Science: Potential intermediate for creating specialty polymers or functional materials with specific heterocyclic properties.

Basic Information

Product Name	1(2H)-Pyrimidinecarbonyl Chloride, 3-Ethyltetrahydro-2,4-Dioxo- (9Ci)
CAS No.	72820-56-5
Molecular Formula	C7H9ClN2O3
Molecular Weight	204.61 g/mol
Synonyms	3-Ethyltetrahydro-2,4-dioxo-1(2H)-pyrimidinecarbonyl chloride; 3-Ethyl-2,4-dioxotetrahydro-1(2H)-pyrimidinecarbonyl chloride; 1(2H)-Pyrimidinecarbonyl chloride, 3-ethyltetrahydro-2,4-dioxo-; Tetrahydro-2,4-dioxo-3-ethyl-1(2H)-pyrimidinecarbonyl chloride; 3-Ethylbarbituric-5-carbonyl chloride; 5-(Chlorocarbonyl)-3-ethylbarbituric acid
EINECS	Contact for details

Quality Control

Our production of 1(2H)-Pyrimidinecarbonyl Chloride adheres to strict in-process controls to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against established specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.