Description

4-Amino-4-Dihydrospectinomycin is a key semi-synthetic derivative of the aminocyclitol antibiotic spectinomycin. This compound serves as a critical intermediate in the synthesis of novel, more potent antibiotic agents, addressing the growing need for new therapeutic options against resistant bacterial strains. It is primarily utilized by pharmaceutical R&D departments, fine chemical manufacturers, and academic research institutions focused on antimicrobial development and chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of next-generation aminocyclitol antibiotics with improved efficacy and spectrum of activity.
• Antimicrobial Research: Used in biochemical and microbiological studies to investigate structure-activity relationships (SAR) and mechanisms of action against bacterial ribosomes.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Synthesis: Employed in custom synthesis and process chemistry for creating specialized chemical libraries and novel molecular entities.
• Veterinary Medicine Development: Investigated for potential applications in developing new antimicrobial treatments for animal health.

Basic Information

Product Name	4-Amino-4-Dihydrospectinomycin
CAS No.	72748-69-7
Molecular Formula	C₁₄H₂₈N₂O₇
Molecular Weight	336.38 g/mol
Synonyms	4-Amino-4-deoxyspectinomycin; 4'-Amino-4'-deoxyspectinomycin; 4-Amino-4-dihydrospectinomycin dihydrochloride; 4-Amino-4-deoxy-dihydrospectinomycin; Spectinomycin 4-amino-4-deoxy derivative; (1R,2S,3S,4R,5R,6S)-4-Amino-2,5,7-trihydroxy-6-methyl-3-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-8-oxabicyclo[3.2.1]octane-4-carbonitrile (related IUPAC form); Aminodihydrospectinomycin
EINECS	Contact for details

Quality Control

Our 4-Amino-4-Dihydrospectinomycin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and stringent control of related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.