Description

24(R/S),25-Epoxycholesterol is a synthetic oxysterol derivative of cholesterol, a key intermediate in the study of sterol metabolism and biosynthesis. This compound is of significant value for pharmaceutical and biochemical research, particularly in investigating the regulatory pathways of cholesterol homeostasis and the biological activity of oxysterols. It is primarily utilized by researchers and manufacturers in the life sciences sector for drug discovery, metabolic pathway analysis, and as a reference standard in analytical chemistry.

Application

• Biochemical Research: A critical tool for studying the enzymatic pathways of cholesterol metabolism, including the roles of cytochrome P450 enzymes.
• Pharmaceutical Development: Serves as a key intermediate or reference compound in the development of drugs targeting cholesterol-related disorders, such as atherosclerosis.
• Cell Signaling Studies: Used to investigate oxysterol-mediated signaling pathways, including their effects on nuclear receptors like LXR (Liver X Receptor).
• Analytical Reference Standard: Employed as a high-purity standard in HPLC, LC-MS, and GC-MS for the quantification and identification of sterols in complex biological matrices.
• Metabolomics: An important metabolite for profiling sterol and lipid metabolic networks in various disease models.

Basic Information

Product Name	24(R/S),25-Epoxycholesterol
CAS No.	72542-49-5
Molecular Formula	C27H44O2
Molecular Weight	400.64 g/mol
Synonyms	24,25-Epoxycholesterol; (24R/S)-24,25-Epoxycholest-5-en-3β-ol; 24,25-Epoxy-cholesterol; 24,25-EC; 5-Cholesten-3β-ol, 24,25-epoxy-; 24,25-Epoxycholest-5-en-3-ol; 24,25-Epoxycholest-5-en-3β-ol; 24,25-Epoxycholest-5-en-3β-ol (racemic)
EINECS	Contact for details

Quality Control

Our 24(R/S),25-Epoxycholesterol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.