Description

9-β-D-Arabinofuranosylguanosine 5'-Triphosphate is a modified nucleoside triphosphate analog, specifically an arabinose-containing derivative of guanosine triphosphate (GTP). This compound is a critical biochemical reagent used in enzymatic studies and nucleic acid research, where it serves as a substrate or inhibitor. It is primarily utilized by researchers and manufacturers in the fields of molecular biology, enzymology, and pharmaceutical development, particularly for investigating viral polymerases and metabolic pathways.

Application

• Biochemical Research: As a substrate for studying the activity and inhibition of DNA and RNA polymerases, especially viral enzymes.
• Antiviral Drug Development: Investigation of nucleoside analog prodrugs and their mechanisms of action against viral infections.
• Enzymology Studies: Used in kinetic assays to understand enzyme specificity and catalytic mechanisms involving GTP analogs.
• Diagnostic Assay Development: Potential component in the formulation of kits for detecting specific enzymatic activities.
• Metabolic Pathway Analysis: Tool for probing cellular signaling pathways and nucleotide metabolism.
• Academic & Pharmaceutical R&D: Fundamental reagent for basic research and high-throughput screening in drug discovery programs.

Basic Information

Product Name	9-β-D-Arabinofuranosylguanosine 5'-Triphosphate
CAS No.	72490-81-4
Molecular Formula	C15H23N5O14P3
Molecular Weight	599.27 g/mol
Synonyms	9-β-D-Arabinofuranosylguanine 5'-triphosphate; AraGTP; 9-β-D-Arabinofuranosylguanosine triphosphate; β-D-Arabinofuranosylguanosine 5'-triphosphate; 1-(β-D-Arabinofuranosyl)guanine 5'-triphosphate; Guanine, 9-(β-D-arabinofuranosyl)-, 5'-(tetrahydrogen triphosphate); 9-(β-D-Arabinofuranosyl)guanosine-5'-triphosphate
EINECS	Contact for details

Quality Control

Our 9-β-D-Arabinofuranosylguanosine 5'-Triphosphate is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Biological Activity	Tested in standard enzymatic assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.