Description

2'-Deoxycoformycin 5'-Phosphate is a chemically modified nucleotide analog of significant interest in biochemical and pharmaceutical research. This compound is valued for its role as a potent inhibitor of adenosine deaminase, a key enzyme in purine metabolism. It is primarily utilized by research institutions and pharmaceutical developers focused on oncology, immunology, and enzymology studies. The product is supplied to meet the stringent purity requirements of advanced life science applications.

Application

• Biochemical Research: Used as a high-purity reference standard and inhibitor in enzymatic studies of adenosine deaminase and related purine salvage pathways.
• Pharmaceutical Development: Serves as a critical intermediate or active pharmaceutical ingredient (API) in the research and development of novel therapeutic agents, particularly in oncology.
• Cell Biology & Immunology: Employed in in vitro studies to modulate adenosine levels, affecting lymphocyte function and immune response for investigative purposes.
• Diagnostic Reagent Manufacturing: Acts as a key component in the formulation of diagnostic kits and assays designed to measure adenosine deaminase activity.
• Academic Research: Utilized in university and institutional labs for fundamental research into nucleotide metabolism, enzyme kinetics, and drug mechanism of action.

Basic Information

Product Name	2'-Deoxycoformycin 5'-Phosphate
CAS No.	72490-67-6
Molecular Formula	C11H15N4O7P
Molecular Weight	346.24 g/mol
Synonyms	Pentostatin 5'-Phosphate; 2'-Deoxycoformycin 5'-Monophosphate; (R)-3-(2-Deoxy-β-D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol 5'-Phosphate; DCF 5'-Phosphate; Co-vidarabine 5'-phosphate; 2'-DCF 5'-Phosphate; ADA Inhibitor 5'-Phosphate
EINECS	Contact for details

Quality Control

Every batch of 2'-Deoxycoformycin 5'-Phosphate is manufactured and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and development applications. Comprehensive analytical testing, including HPLC for purity and identity confirmation, is performed. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee traceability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.