Description

1-Cyclohexene-1-Carbonyl Chloride, 6-Methyl-, (R)- (9Ci) is a high-value, chiral building block and key synthetic intermediate in advanced organic chemistry. Its specific stereochemistry and reactive acid chloride functional group make it indispensable for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of enantiomerically pure drugs targeting the central nervous system, metabolic disorders, and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its chiral structure can contribute to higher efficacy and environmental selectivity.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in academic and industrial research focused on developing new asymmetric synthetic methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrances, flavors, and other specialty chemicals requiring defined stereochemistry.
• Peptide Mimetics & PROTACs: Utilized as a coupling agent or core structural element in the design of peptide analogs and proteolysis-targeting chimeras (PROTACs) for drug discovery.

Basic Information

Product Name	1-Cyclohexene-1-Carbonyl Chloride, 6-Methyl-, (R)- (9Ci)
CAS No.	72233-49-9
Molecular Formula	C8H11ClO
Molecular Weight	158.62 g/mol
Synonyms	(R)-6-Methyl-1-cyclohexene-1-carbonyl chloride; (R)-2-Methyl-2-cyclohexenecarbonyl chloride; (R)-α-Methyl-δ²-cyclohexene-1-carbonyl chloride; (R)-1-Cyclohexene-1-carboxylic acid, 6-methyl-, chloride; (R)-6-Methylcyclohex-1-enecarboxylic acid chloride; (R)-6-Methyl-1-cyclohexenecarboxylic acid chloride; (R)-2-Methyl-2-cyclohexene-1-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 1-Cyclohexene-1-Carbonyl Chloride, 6-Methyl-, (R)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. All materials are characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; therefore, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and away from incompatible materials. For long-term storage, consider refrigeration (2-8°C).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.