Description

1-Cyclohexene-1-Carbonyl Chloride, 4-(1-Methylethyl)-, (S)- (9Ci) is a high-value, chiral organic intermediate characterized by its reactive acid chloride functional group and specific stereochemistry. This compound is critical for introducing the (S)-4-isopropylcyclohex-1-ene-1-carboxylic acid moiety into complex molecular architectures with precise stereocontrol. It is primarily sought after by research and development teams in the pharmaceutical and advanced agrochemical sectors for the synthesis of novel active ingredients, where its unique structure enables the creation of enantiomerically pure products.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of chiral drug candidates, particularly in therapeutic areas requiring specific stereochemistry for efficacy and safety.
• Agrochemical Synthesis: Used in the research and production of advanced, enantiomerically pure pesticides and herbicides to enhance target specificity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where the isopropylcyclohexene scaffold is required.
• Material Science Research: Investigated as a monomer or modifying agent for polymers with specific optical or mechanical properties.

Basic Information

Product Name	1-Cyclohexene-1-Carbonyl Chloride, 4-(1-Methylethyl)-, (S)- (9Ci)
CAS No.	72233-48-8
Molecular Formula	C10H15ClO
Molecular Weight	186.68 g/mol
Synonyms	(S)-4-Isopropylcyclohex-1-ene-1-carbonyl chloride; (S)-p-Isopropyl-1-cyclohexene-1-carboxylic acid chloride; (S)-1-Cyclohexene-1-carbonyl chloride, 4-(1-methylethyl)-; (4S)-4-(1-Methylethyl)-1-cyclohexene-1-carbonyl chloride; (S)-4-Isopropyl-1-cyclohexene-1-carboxylic acid chloride; L-4-Isopropylcyclohex-1-enecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Our production of 1-Cyclohexene-1-Carbonyl Chloride, 4-(1-Methylethyl)-, (S)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is analyzed using advanced techniques including chiral HPLC, NMR, and GC to confirm identity, enantiomeric excess, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at recommended temperatures (typically 2-8°C or as specified on the label). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.