Description

2'-Bromo-2'-Deoxyuridine is a halogenated nucleoside analog, a crucial building block in biochemical and pharmaceutical research. This compound is valued for its ability to incorporate into DNA, making it a vital tool for studying cellular processes, DNA synthesis, and as a potential precursor in antiviral and anticancer agent development. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in molecular biology, oncology research, and nucleoside chemistry.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to DNA synthesis and repair.
• Antiviral/Anticancer Research: Serves as a key intermediate in the synthesis of novel nucleoside-based therapeutic agents.
• Molecular Biology: Employed in cell proliferation assays and as a marker for DNA synthesis (e.g., in BrdU assays for detecting replicating cells).
• Radiochemistry: Can be used as a precursor for the synthesis of radiolabeled compounds for diagnostic imaging or tracer studies.
• Nucleoside Chemistry: A fundamental starting material for the chemical modification and development of novel nucleoside analogs.

Basic Information

Product Name	2'-Bromo-2'-Deoxyuridine
CAS No.	72218-68-9
Molecular Formula	C9H11BrN2O5
Molecular Weight	307.10 g/mol
Synonyms	5-Bromo-2'-deoxyuridine; BrdU; 5-BrdU; 5-Bromo-2'-deoxyuridine; Broxuridine; BUdR; NSC 38297; 2'-Deoxy-5-bromouridine; 5-Bromo-1-(2-deoxy-β-D-ribofuranosyl)uracil
EINECS	Contact for details

Quality Control

Our 2'-Bromo-2'-Deoxyuridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture to ensure it meets high-purity standards suitable for research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Melting Point	190°C - 195°C (dec.)
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.