Description

(2S,3S,4R,5R)-n-Ethyl-3,4-Dihydroxy-5-(1-Hydroxy-6-Imino-Purin-9-Yl)Ox Olane-2-Carboxamide is a high-purity, stereochemically defined nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and reference standard for the synthesis of novel antiviral and anticancer agents, where precise molecular configuration is paramount for biological activity. It is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleoside chemistry and targeted therapeutic discovery.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a reference standard and probe in enzymatic studies, metabolic pathway analysis, and structure-activity relationship (SAR) investigations.
• Preclinical Development: Serves as an active pharmaceutical ingredient (API) starting material for formulation studies and pharmacological evaluation.
• Process Chemistry: Employed in route scouting and optimization for the scalable synthesis of complex nucleoside derivatives.
• Diagnostic Reagent Manufacturing: Potential component in the synthesis of labeled compounds for diagnostic assays and imaging agents.

Basic Information

Product Name	(2S,3S,4R,5R)-n-Ethyl-3,4-Dihydroxy-5-(1-Hydroxy-6-Imino-Purin-9-Yl)Ox Olane-2-Carboxamide
CAS No.	72209-27-9
Molecular Formula	C₁₂H₁₆N₆O₆
Molecular Weight	340.29 g/mol
Synonyms	N-Ethyl-3',4'-dihydroxy-5'-(1-hydroxy-6-imino-purin-9-yl)oxolane-2-carboxamide; 6-Imino-9-[(2S,3S,4R,5R)-5-[(ethylcarbamoyl)methyl]-3,4-dihydroxyoxolan-2-yl]-1H-purin-1-ol; Acyclovir N-ethyl carboxamide derivative; Nucleoside analog 72209-27-9; 1,9-Dihydro-9-[(2S,3S,4R,5R)-5-[(ethylamino)carbonyl]-3,4-dihydroxy-2-tetrahydrofuranyl]-6H-purin-6-imin-1-ol
EINECS	Contact for details

Quality Control

Every batch of (2S,3S,4R,5R)-n-Ethyl-3,4-Dihydroxy-5-(1-Hydroxy-6-Imino-Purin-9-Yl)Ox Olane-2-Carboxamide is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and stereochemical integrity. Our products are suitable for research and development applications, with specifications aligned with industry standards for fine chemicals. Certificates of Analysis (COA) detailing batch-specific results from HPLC, NMR, and chiral analysis are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (2S,3S,4R,5R isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.