Description

Pregn-5-Ene-3β,8,11α,12β,14β,20-Hexol 3,11,12,20-Tetraacetate is a high-purity, multi-hydroxylated pregnane derivative, serving as a critical advanced intermediate in the synthesis of complex steroid-based pharmaceuticals and bioactive molecules. Its precise stereochemistry and functionalization make it an invaluable building block for research and development in medicinal chemistry, enabling the targeted modification of steroid scaffolds. This compound is essential for pharmaceutical manufacturers, research institutions, and fine chemical producers focused on developing novel therapeutic agents, particularly in the fields of endocrinology and oncology.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel steroid drugs and hormone analogs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new bioactive compounds targeting steroid receptors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating steroid biosynthesis pathways and enzyme inhibition.
• Fine Chemical Synthesis: A versatile starting material for the custom synthesis of specialized steroid derivatives for academic and industrial research.

Basic Information

Product Name	Pregn-5-Ene-3β,8,11α,12β,14β,20-Hexol 3,11,12,20-Tetraacetate
CAS No.	72173-04-7
Molecular Formula	C₂₉H₄₂O₁₀
Molecular Weight	550.64 g/mol
Synonyms	3β,8,11α,12β,14β,20-Hexahydroxypregn-5-ene 3,11,12,20-Tetraacetate; 3β,8,11α,12β,14β,20-Hexahydroxypregn-5-en-3,11,12,20-tetraacetate; 3,11,12,20-Tetraacetylpregn-5-ene-3β,8,11α,12β,14β,20-hexol; Pregn-5-ene-3β,8,11α,12β,14β,20-hexaol, 3,11,12,20-tetraacetate; 3β,8,11α,12β,14β,20-Hexahydroxy-pregn-5-ene 3,11,12,20-Tetraacetate; 72173-04-7
EINECS	Contact for details

Quality Control

Our Pregn-5-Ene-3β,8,11α,12β,14β,20-Hexol 3,11,12,20-Tetraacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.