Description

3-Methyl Adenosine p-Toluenesulfonate Salt is a chemically modified nucleoside derivative where the adenosine base is methylated at the 3-position and isolated as a stable p-toluenesulfonate salt. This compound is significant as a key biochemical tool and a potential synthetic intermediate in the development of nucleoside-based therapeutics and research probes. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and fine chemical manufacturers focused on antiviral drug discovery, RNA metabolism studies, and the synthesis of novel nucleotide analogs.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel nucleoside analogs for antiviral and anticancer drug discovery programs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to RNA methylation, processing, and adenosine deaminase activity.
• Reference Standard: Employed as an analytical standard in HPLC or LC-MS methods for quality control and metabolic studies of methylated nucleosides.
• Life Science Reagents: Incorporated into the development of specialized kits and reagents for epigenetics and molecular biology research.
• Chemical Biology Probes: Utilized in the design of activity-based probes to study methyltransferase enzymes and their roles in cellular pathways.

Basic Information

Product Name	3-Methyl Adenosine p-Toluenesulfonate Salt
CAS No.	72055-63-1
Molecular Formula	C18H23N5O7S
Molecular Weight	453.47 g/mol
Synonyms	3-Methyladenosine Tosylate; 3-Methyladenosine p-Toluenesulfonate; 3-Methyladenosine 4-Methylbenzenesulfonate; 3-Methyl-9-β-D-ribofuranosyladenine p-Toluenesulfonate; N3-Methyladenosine Tosylate Salt; 3-Me-Ado Tosylate; 3-Methyladenosine TsOH Salt; 72055-63-1
EINECS	Contact for details

Quality Control

Every batch of 3-Methyl Adenosine p-Toluenesulfonate Salt is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We provide full traceability and Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, typically assessed by HPLC, NMR, and mass spectrometry. Our quality commitment ensures the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.