Description

2'-Deoxyadenosine-5'-Diphosphate Disodium Salt is a high-purity nucleotide derivative essential for biochemical research and pharmaceutical development. This compound serves as a critical building block and substrate in enzymatic studies, particularly those involving DNA synthesis and repair mechanisms. It is primarily utilized by research institutions, diagnostic kit manufacturers, and biotechnology companies engaged in molecular biology, enzymology, and nucleotide-based therapeutic discovery.

Application

• Enzymatic Substrate: Used as a key substrate for DNA polymerases, reverse transcriptases, and other nucleic acid-modifying enzymes in kinetic and mechanistic studies.
• Biochemical Research: Essential for in vitro DNA synthesis, PCR optimization, and investigations into nucleotide metabolism and signaling pathways.
• Diagnostic Reagent Manufacturing: Incorporated into enzyme-based assay kits for clinical diagnostics and life science research tools.
• Pharmaceutical Intermediate: Serves as a precursor in the synthesis of nucleotide analogs and prodrugs for potential antiviral or anticancer applications.
• Cell Culture & Metabolism Studies: Utilized in metabolic labeling experiments and to study the role of deoxyribonucleotides in cell proliferation and apoptosis.

Basic Information

Product Name	2'-Deoxyadenosine-5'-Diphosphate Disodium Salt
CAS No.	72003-83-9
Molecular Formula	C10H13N5O9P2Na2
Molecular Weight	471.16 g/mol
Synonyms	dADP Disodium Salt; 2'-Deoxyadenosine 5'-(trihydrogen diphosphate) disodium salt; Deoxyadenosine diphosphate disodium; dADP-Na2; 5'-dADP Na2; Adenosine, 2'-deoxy-, 5'-(trihydrogen diphosphate), disodium salt; Deoxyadenosine-5'-diphosphate disodium
EINECS	Contact for details

Quality Control

Every batch of our 2'-Deoxyadenosine-5'-Diphosphate Disodium Salt is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We adhere to stringent in-house specifications suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	6.0 - 8.0
Endotoxin	< 10 EU/mg (if specified)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.