Description

Adenosine 5'-Triphosphate, Periodate Oxidized Sodium Salt is a chemically modified nucleotide analog, specifically the periodate-oxidized derivative of ATP. This modification is critical for its primary function as a potent and irreversible inhibitor of ATP-dependent enzymes, making it an essential tool for biochemical research and diagnostic applications. It is primarily utilized by researchers in enzymology, molecular biology, and by manufacturers of in-vitro diagnostic kits requiring precise enzyme regulation.

Application

• Enzyme Inhibition Studies: Acts as an irreversible inhibitor for kinases, ATPases, and other ATP-binding enzymes to study reaction mechanisms and active sites.
• Diagnostic Reagent Manufacturing: A key component in the formulation of specific diagnostic assays and kits that require controlled inhibition of enzymatic pathways.
• Biochemical Research: Used as a substrate analog to probe energy transduction processes, signal transduction pathways, and nucleotide-binding protein functions.
• Pharmaceutical Development: Employed in high-throughput screening (HTS) to identify potential drug candidates that target ATP-binding pockets of disease-relevant enzymes.

Basic Information

Product Name	Adenosine 5'-Triphosphate, Periodate Oxidized Sodium Salt
CAS No.	71997-40-5
Molecular Formula	C10H12N5Na3O13P3
Molecular Weight	605.10 g/mol
Synonyms	Periodate-Oxidized ATP; oATP; Oxidized Adenosine Triphosphate; 2',3'-Dialdehyde ATP; Adenosine 5'-(tetrahydrogen triphosphate), 2',3'-dialdehyde, sodium salt; ATP dialdehyde; ATP-2',3'-dialdehyde sodium salt
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and diagnostic use. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and activity. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water, buffer solutions
Biological Activity	Inhibits ATP-dependent enzymes as specified

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.