Description

Barnidipine is a potent and selective dihydropyridine-class calcium channel blocker. This compound is significant for its role as a key pharmaceutical intermediate and active pharmaceutical ingredient (API) in the development and production of antihypertensive medications. It is primarily needed by pharmaceutical manufacturers, research institutions, and chemical suppliers serving the global life sciences sector.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of finished antihypertensive drug formulations.
• Active Pharmaceutical Ingredient (API): Used as the core therapeutic agent in the manufacture of calcium channel blocker medications.
• Hypertension Research: Employed in preclinical and clinical research studies focused on cardiovascular diseases.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.
• Process Development: Applied in the scaling and optimization of synthetic routes within pharmaceutical R&D.

Basic Information

Product Name	Barnidipine
CAS No.	71863-55-3
Molecular Formula	C27H29N3O6
Molecular Weight	491.54 g/mol
Synonyms	Barnidipine Hydrochloride; Mepirodipine; YM-09730-5; (±)-Barnidipine; (RS)-Barnidipine; 3-(1-Benzyl-3-piperidyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate; 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-(1-benzyl-3-piperidinyl) ester 5-methyl ester
EINECS	Contact for details

Quality Control

Our Barnidipine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric humidity.

Specification

Item	Specification
Appearance	Yellow to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.