Description

11 β-Chloromethylestradiol is a high-purity, synthetic steroid derivative of estradiol, a key intermediate in advanced pharmaceutical research and development. Its primary value lies in its role as a versatile building block for creating novel therapeutic agents, particularly in the fields of endocrinology and oncology. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology industries who are developing targeted hormone therapies and conducting structure-activity relationship (SAR) studies. The product is supplied under strict quality control to ensure consistency and reliability for critical applications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel steroidal drugs and targeted therapeutic agents.
• Hormone Research: Used in biochemical and pharmacological studies to investigate estrogen receptor interactions and signaling pathways.
• Drug Discovery: Serves as a key scaffold for medicinal chemists in the design and development of new chemical entities (NCEs) for cancer and endocrine disorders.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Academic Research: Utilized in university and institutional labs for advanced studies in steroid chemistry and molecular biology.
• Bioconjugation: The chloromethyl group offers a reactive site for conjugation with other molecules, such as proteins or fluorophores, for diagnostic or targeted delivery applications.

Basic Information

Product Name	11 β-Chloromethylestradiol
CAS No.	71794-60-0
Molecular Formula	C19H25ClO2
Molecular Weight	320.85 g/mol
Synonyms	11β-(Chloromethyl)estradiol; 11β-Chloromethylestra-1,3,5(10)-triene-3,17β-diol; Estra-1,3,5(10)-triene-3,17-diol, 11-(chloromethyl)-, (11β,17β)-; 11β-Chloromethyl-17β-estradiol; 11-Chloromethylestradiol
EINECS	Contact for details

Quality Control

Our 11 β-Chloromethylestradiol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing specific results for purity, identity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.