Description

2-Methoxy-5-Nitrophenyl Isothiocyanate is a versatile aromatic isothiocyanate derivative, primarily valued as a key synthetic intermediate for constructing complex heterocyclic and functionalized molecular architectures. Its core value proposition lies in its dual reactive sites—the electrophilic isothiocyanate group and the electron-deficient aromatic ring—which enable precise derivatization and labeling in advanced chemical synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active ingredients, fluorescent probes, and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, leveraging its reactivity to create bioactive molecules.
• Bioconjugation & Labeling Reagent: Acts as a coupling agent for modifying peptides, proteins, and other biomolecules, useful in assay development and diagnostic applications.
• Dye & Pigment Manufacturing: Employed as a precursor in the synthesis of specialized azo dyes and pigments for high-performance applications.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new organic reactions and creating novel chemical entities.
• Material Science: Used in the surface functionalization of polymers and nanoparticles to impart specific chemical properties.

Basic Information

Product Name	2-Methoxy-5-Nitrophenyl Isothiocyanate
CAS No.	71793-51-6
Molecular Formula	C8H6N2O3S
Molecular Weight	210.21 g/mol
Synonyms	5-Nitro-2-methoxyphenyl isothiocyanate; 2-Methoxy-5-nitrobenzenisothiocyanate; 1-Isothiocyanato-2-methoxy-5-nitrobenzene; (2-Methoxy-5-nitrophenyl)isothiocyanate; NSC 403796; 5-Nitro-o-anisyl isothiocyanate; 2-Methoxy-5-nitro-phenyl isothiocyanate
EINECS	Contact for details

Quality Control

Our 2-Methoxy-5-Nitrophenyl Isothiocyanate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with your research or manufacturing specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.