Description

16-Bromoestrone is a halogenated derivative of the natural estrogen steroid, estrone, serving as a key synthetic intermediate in advanced organic and medicinal chemistry. This compound is valued for its role in introducing a bromine atom at the C-16 position, enabling further functionalization and structure-activity relationship studies. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel steroid-based therapeutics, hormone receptor modulators, and biochemical probes.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a precursor or reference standard in studies involving estrogen metabolism, hormone signaling pathways, and receptor binding assays.
• Organic Synthesis: Serves as a versatile intermediate for further chemical modifications, including cross-coupling reactions, to create libraries of steroid analogs.
• Academic & R&D: Employed in university and industrial research laboratories for method development and exploratory chemistry projects.

Basic Information

Product Name	16-Bromoestrone
CAS No.	71765-95-2
Molecular Formula	C18H21BrO2
Molecular Weight	349.27 g/mol
Synonyms	16-Bromo-estra-1,3,5(10)-trien-3-ol-17-one; 16-Bromo-3-hydroxyestra-1,3,5(10)-trien-17-one; 16-Bromo-1,3,5(10)-estratrien-3-ol-17-one; 16-Bromo-E1; 16-Br-Estrone; 16-Bromo-oestrone
EINECS	Contact for details

Quality Control

Our 16-Bromoestrone is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.