Description

2-Mercapto-2-Methyl-4-Oxopentanoic Acid Chloride is a specialized organosulfur compound featuring both a highly reactive acid chloride group and a thiol functionality. This dual reactivity makes it a valuable key intermediate for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, peptide mimetics, and functional materials where precise molecular assembly is critical.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly those targeting enzyme inhibition or requiring specific thioether linkages.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators that incorporate sulfur-based bioactive moieties.
• Peptide & Protein Modification: Employed for the site-specific introduction of thiol-reactive groups or for creating custom cross-linking agents in bioconjugation chemistry.
• Polymer Chemistry: Serves as a monomer or functionalization agent for creating specialty polymers with unique degradation profiles or adhesion properties.
• Material Science Research: Utilized in the development of advanced materials, such as self-assembled monolayers (SAMs) or functional coatings on surfaces.
• Chemical Biology Probes: Acts as a precursor for synthesizing activity-based probes used to study enzyme function and mechanism in biological systems.

Basic Information

Product Name	2-Mercapto-2-Methyl-4-Oxopentanoic Acid Chloride
CAS No.	71735-69-8
Molecular Formula	C6H9ClO2S
Molecular Weight	180.65 g/mol
Synonyms	2-Methyl-2-sulfanyl-4-oxopentanoyl chloride; 4-Oxo-2-mercapto-2-methylpentanoyl chloride; 2-Mercapto-2-methyl-4-oxovaleric acid chloride; 2-Methyl-2-mercapto-4-oxopentanoic acid chloride; 4-Oxo-2-methyl-2-sulfanylpentanoyl chloride; 2-Methyl-2-thiol-4-oxopentanoic acid chloride; (2-Mercapto-2-methyl-4-oxopentanoyl) chloride
EINECS	Contact for details

Quality Control

Our production of 2-Mercapto-2-Methyl-4-Oxopentanoic Acid Chloride adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, strong oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.