Description

Cyclopropanecarboxylic Acid, 2-(Chlorocarbonyl)-, Ethyl Ester, cis- (9Ci) is a high-purity, cis-configured cyclopropane derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in the reactive acid chloride and ester functionalities, which enable precise and efficient construction of complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of proprietary drug candidates, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the cyclopropane ring contributes to biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel polymers and functional materials with specific stereochemical properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, particularly in stereoselective reactions and ring-forming transformations.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-(Chlorocarbonyl)-, Ethyl Ester, cis- (9Ci)
CAS No.	71666-00-7
Molecular Formula	C7H9ClO3
Molecular Weight	176.60 g/mol
Synonyms	cis-2-(Chlorocarbonyl)cyclopropanecarboxylic Acid Ethyl Ester; Ethyl cis-2-(Chlorocarbonyl)cyclopropanecarboxylate; cis-1,2-Cyclopropanedicarboxylic Acid 1-Chloride 2-Ethyl Ester; (1R,2S)-rel-2-(Chlorocarbonyl)cyclopropanecarboxylic Acid Ethyl Ester; Cyclopropane-1,2-dicarboxylic Acid 1-Chloride 2-Ethyl Ester, cis-; (1S,2R)-rel-2-(Chlorocarbonyl)cyclopropanecarboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our production of Cyclopropanecarboxylic Acid, 2-(Chlorocarbonyl)-, Ethyl Ester, cis- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing parameters such as chiral purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% cis-isomer
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.