Description

3-Bromoisonicotinoyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its value lies in its role as a key building block for introducing the 3-bromoisonicotinoyl moiety into target molecules, enabling the creation of complex heterocyclic compounds. This product is critically needed by research and development laboratories, as well as production facilities, in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require the isonicotinoyl scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, metal-organic frameworks (MOFs), and polymers with specific functional properties.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic and Industrial R&D: Fundamental building block in medicinal chemistry programs and process chemistry optimization for scale-up.

Basic Information

Product Name	3-Bromoisonicotinoyl Chloride
CAS No.	71541-33-8
Molecular Formula	C6H3BrClNO
Molecular Weight	220.45 g/mol
Synonyms	3-Bromoisonicotinic acid chloride; 3-Bromo-4-pyridinecarbonyl chloride; 3-Bromopyridine-4-carbonyl chloride; 3-Bromo-4-pyridylcarbonyl chloride; Isonicotinic acid, 3-bromo-, chloride; 4-Pyridinecarbonyl chloride, 3-bromo-; 3-Bromo-4-carbamoylpyridine hydrochloride (precursor related); 71541-33-8
EINECS	Contact for details

Quality Control

Our 3-Bromoisonicotinoyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all relevant specifications. Our quality commitment supports compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and separated from strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.