Description

Efrapeptin D is a potent, naturally occurring peptaibol antibiotic complex produced by the fungus Tolypocladium. This compound is valued for its specific inhibitory activity against mitochondrial F1F0-ATPase, making it a critical research tool in biochemistry and cell biology. It is primarily utilized by researchers in pharmaceutical development, agrochemical discovery, and academic institutions studying bioenergetics and ion transport mechanisms.

Application

• Biochemical Research: As a specific inhibitor of mitochondrial and bacterial F1F0-ATP synthase for mechanistic studies.
• Pharmaceutical Discovery: Investigation of its antimicrobial and potential anticancer properties in drug development pipelines.
• Agrochemical Research: Exploration of its insecticidal and antifungal activities for novel crop protection agents.
• Cell Biology Studies: Tool compound for probing cellular energy metabolism, ATP production, and ion homeostasis.
• Enzymology: Used in assays to study ATPase enzyme kinetics and inhibition profiles.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratories.

Basic Information

Product Name	Efrapeptin D
CAS No.	71503-60-1
Molecular Formula	C58H95N15O14
Molecular Weight	1210.5 g/mol
Synonyms	Efrapeptin D; Antibiotic A23871D; Peptaibol A23871D; ATPase inhibitor, efrapeptin-type; Tolypocladium antibiotic complex D; Leu-Aib-Iva-Gly-Aib-Aib-Aib-Gln-Aib-Iva-Aib-Gly-Leu-Aib-Glyol; A23871D
EINECS	Contact for details

Quality Control

Our Efrapeptin D is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic nature, the container should be allowed to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Biological Activity (ATPase Inhibition)	IC50 provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.