Description

(22R)-6α,7α-Epoxy-5,12β,22-Trihydroxy-1-Oxo-5α-Ergosta-2,24-Dien-26-Oic Acid δ-Lactone is a complex ergostane-type steroidal lactone, a key intermediate and reference standard in advanced pharmaceutical research and development. Its intricate polycyclic structure with multiple oxygen functionalities makes it a valuable scaffold for the synthesis of novel bioactive compounds and for analytical method development. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly those focused on steroid chemistry, metabolic pathway studies, and the development of new therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control, method validation, and regulatory compliance in drug development and manufacturing.
• Biochemical Research: Serves as a critical intermediate or probe in studying steroid biosynthesis, enzyme inhibition, and metabolic pathways.
• Fine Chemical Synthesis: Acts as a sophisticated building block for the semi-synthesis of novel steroidal derivatives with potential pharmacological activity.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic chemistry, natural product chemistry, and medicinal chemistry.
• Analytical Method Development: Employed to develop and calibrate advanced analytical techniques such as HPLC, LC-MS, and NMR for steroidal compound analysis.

Basic Information

Item	Details
Product Name	(22R)-6α,7α-Epoxy-5,12β,22-Trihydroxy-1-Oxo-5α-Ergosta-2,24-Dien-26-Oic Acid δ-Lactone
CAS No.	71473-21-7
Molecular Formula	C₂₈H₃₈O₇
Molecular Weight	486.60 g/mol
Synonyms	6α,7α-Epoxy-5,12β,22-trihydroxy-1-oxo-5α-ergosta-2,24-dien-26-oic acid δ-lactone; (22R)-Ergosta-2,24-dien-26-oic acid derivative; 5α-Ergosta-2,24-dien-26-oic acid lactone; Steroidal epoxy lactone; Ergostane lactone intermediate; 71473-21-7; UNII-8VZU8B8WQI
EINECS	Contact for details

Quality Control

Every batch of (22R)-6α,7α-Epoxy-5,12β,22-Trihydroxy-1-Oxo-5α-Ergosta-2,24-Dien-26-Oic Acid δ-Lactone is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by HPLC, NMR, and MS. Our quality commitment ensures the material meets the stringent requirements for use as a pharmaceutical reference standard and high-purity research chemical. Custom purity grades and analytical packages are available to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.