Description

26-Aminocholesterol is a functionalized sterol derivative where an amino group is introduced at the 26-position of the cholesterol side chain. This modification is critical for creating advanced biochemical probes and pharmaceutical intermediates with targeted biological activity. It is primarily utilized by researchers and manufacturers in the life sciences sector for applications ranging from drug discovery to the synthesis of novel lipid-based conjugates. The compound 26-Aminocholesterol CAS NO 71472-94-1 serves as a versatile building block for developing high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of novel steroid-based therapeutics and drug candidates targeting metabolic pathways.
• Biochemical Research: Used as a precursor for creating fluorescent or affinity-tagged cholesterol analogs to study lipid trafficking, membrane biology, and cellular signaling.
• Lipid Conjugate Synthesis: Enables the development of cholesterol-labeled peptides, proteins, or oligonucleotides for diagnostic and delivery applications.
• Material Science: Serves as a functional monomer or additive in the development of specialized polymers and biomaterials with sterol-based properties.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling in steroid chemistry.

Basic Information

Product Name	26-Aminocholesterol
CAS No.	71472-94-1
Molecular Formula	C27H47NO
Molecular Weight	401.67 g/mol
Synonyms	26-Amino-5-cholesten-3β-ol; 3β-Hydroxy-26-aminocholest-5-ene; Cholesterol-26-amine; 26-Aminocholest-5-en-3β-ol; (3β)-26-Aminocholest-5-en-3-ol; Aminocholesterol (26-); 26-NH2-Cholesterol
EINECS	Contact for details

Quality Control

Our 26-Aminocholesterol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.