Description

Tetracenomycin C is a significant member of the anthracycline family of antibiotics, known for its complex aromatic polyketide structure. This compound serves as a crucial intermediate and reference standard in the research and development of novel antitumor agents and antibiotics. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on oncology and infectious disease. The product is supplied with full analytical documentation to support critical research and development workflows.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel anthracycline-based chemotherapeutic agents.
• Biological Activity Studies: Used as a reference compound to study mechanisms of action, including DNA intercalation and topoisomerase inhibition.
• Antibiotic Research: Serves as a model compound for investigating the biosynthesis and structure-activity relationships (SAR) of tetracyclic polyketide antibiotics.
• Analytical Standard: Employed as a high-purity certified reference material (CRM) for HPLC, LC-MS, and NMR method development and validation in quality control laboratories.
• Biochemical Pathway Analysis: Used in studies exploring polyketide synthase (PKS) enzymes and genetic engineering of antibiotic-producing microorganisms.

Basic Information

Product Name	Tetracenomycin C
CAS No.	71135-22-3
Molecular Formula	C22H16O9
Molecular Weight	424.36 g/mol
Synonyms	Tetracenomycin C; 5,12-Dihydroxy-4a,10a-dihydro-4H,6H-tetracene-2,8-dicarboxylic acid, 4,4a,5,6,9,10,10a,12-octahydro-6,9,10-trihydroxy-1,11-dimethyl-, γ-lactone; Tcm C; Antibiotic Tcm C; NSC 687488
EINECS	Contact for details

Quality Control

Our Tetracenomycin C is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant industry standards for reference materials, ensuring data integrity for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.