Description

3-Cyclobutylpropanoyl Chloride is a versatile acid chloride intermediate characterized by its reactive carbonyl chloride group and cyclobutyl moiety. This compound matters for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing cyclobutane rings for conformational restriction.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides where the cyclobutyl group can influence biological activity and environmental fate.
• Peptide Mimetics & Drug Discovery: Employed to introduce the cyclobutylpropanoyl moiety into peptide backbones or small molecule scaffolds to modulate potency, selectivity, and metabolic stability.
• Material Science Monomer: Serves as a reactive monomer or cross-linking agent in the synthesis of specialized polymers with unique thermal or mechanical properties.
• Ligand & Catalyst Development: Used to prepare novel ligands for asymmetric catalysis or metal-organic frameworks (MOFs).
• Fine Chemical Production: Acts as an acylating agent in multistep synthetic routes for flavors, fragrances, and advanced organic compounds.

Basic Information

Product Name	3-Cyclobutylpropanoyl Chloride
CAS No.	71037-57-5
Molecular Formula	C7H11ClO
Molecular Weight	146.62 g/mol
Synonyms	3-Cyclobutylpropionyl Chloride; Cyclobutylpropionyl Chloride; 3-Cyclobutylpropanoyl Chloride; 3-Cyclobutylpropanoic Acid Chloride; Cyclobutane-1-propanoyl Chloride; 71037-57-5; 3-Cyclobutylpropionic Acid Chloride; Cyclobutylpropanoic Acid Chloride
EINECS	Contact for details

Quality Control

Our 3-Cyclobutylpropanoyl Chloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.