Description

9-(5-o-Phosphono-β-D-Arabinofuranosyl)-9H-Purin-6-Aminedisodium Salt is a chemically modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and intermediate for the synthesis of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical manufacturers, and biotechnology companies engaged in the development of nucleotide-based drugs. Its precise chemical structure enables targeted modifications in drug design, offering pathways to more effective and selective treatments.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleotide analogs for antiviral medications.
• Antiviral Drug Research: Used in R&D for developing treatments against viral infections by targeting viral polymerase enzymes.
• Oncology Research: Investigated as a building block for prodrugs and chemotherapeutic agents designed to inhibit cancer cell proliferation.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and DNA/RNA synthesis.
• Prodrug Development: Utilized to create more bioavailable or targeted forms of active pharmaceutical ingredients (APIs).
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	9-(5-o-Phosphono-β-D-Arabinofuranosyl)-9H-Purin-6-Aminedisodium Salt
CAS No.	71002-10-3
Molecular Formula	C10H11N5Na2O7P
Molecular Weight	389.17 g/mol
Synonyms	9-(5-o-Phosphono-β-D-arabinofuranosyl)-9H-purin-6-amine disodium salt; Vidarabine 5'-monophosphate disodium salt; Ara-AMP disodium salt; 9-β-D-Arabinofuranosyladenine 5'-monophosphate disodium salt; Adenine 9-β-D-arabinofuranoside 5'-(dihydrogen phosphate) disodium salt; 9-(5-Phosphono-β-D-arabinofuranosyl)-9H-purin-6-amine disodium salt; Vidarabine monophosphate disodium; Ara-A 5'-monophosphate disodium
EINECS	Contact for details

Quality Control

Our 9-(5-o-Phosphono-β-D-Arabinofuranosyl)-9H-Purin-6-Aminedisodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent tests for residual solvents and impurities to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
pH (1% Solution)	6.5 - 8.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.