Description

5A-Dihydroaldosterone is a key intermediate and reference standard in steroid chemistry and pharmaceutical research. This compound is critical for studies related to mineralocorticoid receptor activity and the synthesis of related steroid hormones. It is primarily utilized by research institutions and pharmaceutical companies engaged in endocrinology, drug discovery, and analytical method development.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments (HPLC, GC-MS) and the validation of assay methods in quality control laboratories.
• Biochemical Research: Serves as a crucial intermediate or ligand in studies investigating aldosterone metabolism, mineralocorticoid pathways, and related endocrine functions.
• Active Pharmaceutical Ingredient (API) Synthesis: Acts as a key building block in the multi-step synthesis of more complex steroid-based pharmaceutical compounds.
• Metabolite Studies: Employed in clinical and preclinical research to understand the metabolic fate and biological activity of aldosterone and its derivatives.

Basic Information

Product Name	5A-Dihydroaldosterone
CAS No.	70952-53-3
Molecular Formula	C21H30O4
Molecular Weight	346.46 g/mol
Synonyms	5α-Dihydroaldosterone; 18,11-Hemiacetal of 5α-Dihydroaldosterone; 3,20-Dioxo-5α-pregnane-11β,18-epoxy-18,21-diol; 11β,21-Dihydroxy-3,20-dioxo-5α-pregnan-18-al; Aldosterone 5α-Dihydro Derivative
EINECS	Contact for details

Quality Control

Our 5A-Dihydroaldosterone is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our quality systems are designed to support GMP-grade applications and rigorous research standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.