Description

2-Amino-5-Nitrobenzoyl Chloride Monohydrochloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its value lies in its dual functionality, combining a protected amino group with a highly reactive acid chloride, enabling precise molecular construction. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and specialty dyes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex heterocyclic compounds and potential active pharmaceutical ingredients (APIs).
• Peptide Mimetic Synthesis: Used to introduce nitro-substituted benzoyl groups into peptide backbones for structure-activity relationship (SAR) studies.
• Agrochemical Research: Serves as a precursor for developing novel herbicides and pesticides with specific targeting properties.
• Dye and Pigment Manufacturing: Intermediate in the production of azo dyes and other nitro-aromatic based colorants.
• Material Science: Used in the research and development of advanced polymers and liquid crystals.
• Cross-coupling Reactions: Acts as an electrophile in palladium-catalyzed reactions for creating biaryl structures.

Basic Information

Product Name	2-Amino-5-Nitrobenzoyl Chloride Monohydrochloride
CAS No.	70935-73-8
Molecular Formula	C7H6ClN2O3 • HCl
Molecular Weight	249.05 g/mol
Synonyms	5-Nitroanthraniloyl Chloride Hydrochloride; 2-Amino-5-nitrobenzoic acid chloride hydrochloride; Benzoic acid, 2-amino-5-nitro-, chloride, hydrochloride (1:1); 2-Amino-5-nitrobenzoyl chloride HCl; 5-Nitro-2-aminobenzoyl chloride hydrochloride; Anthraniloyl chloride, 5-nitro-, hydrochloride; (2-Amino-5-nitrophenyl)(chloro)methanone hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Nitrobenzoyl Chloride Monohydrochloride is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards, and comprehensive analytical testing is performed, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opened for use to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.