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6-Azido-6-Deoxy-L-Galactose CAS NO 70932-63-7
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CAS No.:70932-63-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
6-Azido-6-Deoxy-L-Galactose is a chemically modified monosaccharide derivative, serving as a crucial click chemistry reagent and synthetic intermediate. Its core value lies in enabling the efficient, bioorthogonal conjugation of galactose moieties to various probes, surfaces, or biomolecules via azide-alkyne cycloaddition. This compound is essential for researchers and manufacturers in glycobiology, pharmaceutical development, and diagnostic reagent production, where precise carbohydrate labeling and functionalization are required.
Application
- Glycoconjugate Synthesis: Key building block for the chemical and enzymatic synthesis of novel glycoproteins, glycolipids, and neoglycoconjugates.
- Click Chemistry Reagent: Used in copper-catalyzed (CuAAC) or strain-promoted (SPAAC) azide-alkyne cycloadditions to label biomolecules with galactose epitopes.
- Metabolic Oligosaccharide Engineering (MOE):strong> Acts as a precursor for metabolic labeling, allowing the incorporation of azide tags into cellular glycans for subsequent visualization or pull-down assays.
- Pharmaceutical Research: Intermediate in the development of carbohydrate-based vaccines, drug delivery systems, and glycomimetic therapeutics.
- Diagnostic Development: Used to create labeled ligands and probes for studying galactose-binding lectins, receptors (e.g., asialoglycoprotein receptor), and carbohydrate-protein interactions.
- Material Science: Functionalization of surfaces (e.g., chips, nanoparticles, polymers) with bioactive galactose residues for biosensing or biocompatibility applications.
- Chemical Biology Tool: Probe for investigating galactose metabolism, glycan biosynthesis pathways, and related biological functions.
Basic Information
| Product Name | 6-Azido-6-Deoxy-L-Galactose |
| CAS No. | 70932-63-7 |
| Molecular Formula | C6H11N3O5 |
| Molecular Weight | 205.17 g/mol |
| Synonyms | 6-Azido-6-deoxy-L-galactopyranose; 6-Azido-6-deoxygalactose; L-Galactose, 6-azido-6-deoxy-; 6-Azidogalactose; 6-N3-Gal; Azidogalactose; 6-Deoxy-6-azido-L-galactose |
| EINECS | Contact for details |
Quality Control
Our 6-Azido-6-Deoxy-L-Galactose is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 2.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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