Description

Fluoroethylguanosine is a modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound matters for its role as a key synthetic intermediate and potential active pharmaceutical ingredient (API) in the creation of novel antiviral and anticancer therapeutics. Industries that need it include pharmaceutical manufacturers, biotechnology research firms, and academic institutions focused on nucleoside chemistry and drug discovery. Its precise structure allows for targeted biochemical interactions, making it a valuable building block for next-generation medicinal compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleotide metabolism and related pathways.
• Antiviral Drug Development: Explored for incorporation into oligonucleotide sequences targeting viral replication mechanisms.
• Oncology Research: Investigated for its potential cytotoxic properties and ability to interfere with cancer cell DNA/RNA synthesis.
• Radiopharmaceuticals: Potential use as a precursor for fluorine-18 (18F) labeled compounds in Positron Emission Tomography (PET) imaging agents.
• Process Development: Utilized in scaling up synthetic routes for GMP-grade production of final drug substances.

Basic Information

Product Name	Fluoroethylguanosine
CAS No.	70650-86-1
Molecular Formula	C12H16FN5O5
Molecular Weight	329.29 g/mol
Synonyms	2'-Deoxy-2'-fluoro-5-ethylguanosine; 5-Ethyl-2'-deoxy-2'-fluoroguanosine; 1-[(2R,3R,4S,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-ethyl-1,2,3,6-tetrahydropyrimidine-2,4-dione; 9-[(2R,3R,4S,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-ethylguanine; Fluoroethyl Guanosine; 2'-F-5-Et-Guo
EINECS	Contact for details

Quality Control

Our Fluoroethylguanosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and impurities to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.