Description

1-Methylisoguanosine is a chemically modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a valuable building block and reference standard in the synthesis of novel therapeutic agents, particularly those targeting neurological and metabolic pathways. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in advanced drug discovery and biochemical studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of adenosine receptor agonists and other nucleoside-based drug candidates.
• Biochemical Research: Used as a reference standard and tool compound in studies of purinergic signaling and nucleotide metabolism.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new analogs with enhanced potency or selectivity.
• Analytical Standard: Serves as a high-purity standard for quality control and method development in analytical laboratories (HPLC, LC-MS).
• Enzyme Substrate/Inhibitor Studies: Investigated for its interaction with various kinases, phosphorylases, and other enzymes involved in nucleotide pathways.

Basic Information

Product Name	1-Methylisoguanosine
CAS No.	70639-65-5
Molecular Formula	C11H15N5O5
Molecular Weight	297.27 g/mol
Synonyms	1-Methylisoguanosine; 1-Methyl-iso-guanosine; 6-Amino-1-methyl-9-β-D-ribofuranosylpurin-2(1H)-one; 1-Methyl-2-oxopurine riboside; 1-Methyl-iso-G; Isoquanosine, 1-methyl-
EINECS	Contact for details

Quality Control

Our 1-Methylisoguanosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.