Description

3'-Amino-3'-Deoxycytidine is a modified nucleoside analog of cytidine, where the 3'-hydroxyl group on the sugar moiety is replaced by an amino group. This structural modification is critical for its role as a key intermediate and building block in the synthesis of novel oligonucleotides and pharmaceutical compounds. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral agents, anticancer therapeutics, and advanced molecular biology tools. The compound's unique structure allows for the exploration of novel mechanisms of action in drug discovery and genetic research.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel nucleoside-based antiviral and anticancer drugs.
• Oligonucleotide Synthesis: Used in the research and development of modified antisense oligonucleotides and siRNA for therapeutic applications.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to investigate nucleic acid metabolism and related pathways.
• Proteomics & Genomics: Acts as a specialized reagent in the study of gene expression, protein-nucleic acid interactions, and diagnostic assay development.
• Academic Research: Utilized in university and institutional labs for fundamental research in medicinal chemistry and molecular biology.

Basic Information

Product Name	3'-Amino-3'-Deoxycytidine
CAS No.	70580-89-1
Molecular Formula	C9H14N4O4
Molecular Weight	242.23 g/mol
Synonyms	3'-Amino-2',3'-dideoxycytidine; 1-(3-Amino-3-deoxy-β-D-ribofuranosyl)cytosine; 3'-Amino-ddC; 3'-Amino-2',3'-dideoxycytidine; 3'-NH2-ddC; 4-Amino-1-((2R,4S,5R)-4-amino-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 3'-Amino-3'-Deoxycytidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and pharmaceutical development. Certificates of Analysis (COA) with detailed specifications are provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.