Description

3'-Azido-3'-Deoxycytidine is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical intermediate and building block for the synthesis of novel antiviral and anticancer agents, particularly in the development of nucleoside reverse transcriptase inhibitors. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors. The product is supplied under stringent quality control to ensure consistency and reliability for sensitive applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of nucleoside-based antiviral drugs, including potential HIV and hepatitis therapeutics.
• Anticancer Research: Investigated as a precursor for prodrugs and novel chemotherapeutic agents targeting DNA synthesis in cancer cells.
• Biochemical Research: Used in molecular biology and enzymology studies to probe nucleotide metabolism and enzyme mechanisms.
• Proteomics & Genomics: Acts as a chemical probe or modifier in the study of nucleic acid interactions and protein-nucleic acid complexes.
• Fine Chemical Synthesis: Serves as a specialized starting material for custom synthesis and the creation of labeled compounds for diagnostic applications.

Basic Information

Product Name	3'-Azido-3'-Deoxycytidine
CAS No.	70580-87-9
Molecular Formula	C9H12N6O4
Molecular Weight	268.23 g/mol
Synonyms	3'-Azido-3'-deoxycytidine; 3'-Azidocytidine; 1-(3-Azido-3-deoxy-β-D-ribofuranosyl)cytosine; 3'-N3-3'-dCyd; AZT-C; Azidodeoxycytidine; NSC 401005
EINECS	Contact for details

Quality Control

Our 3'-Azido-3'-Deoxycytidine is manufactured under a quality management system and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Standard quality parameters include identity confirmation, purity assay, and control of related substances. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.