Description

Arginine Fosfomycin is a stable, water-soluble salt form of the broad-spectrum antibiotic fosfomycin, offering enhanced stability and handling properties. This compound is critical for pharmaceutical manufacturers requiring a reliable and consistent active pharmaceutical ingredient (API) for formulation development. It is primarily utilized in the production of injectable and oral antibiotic preparations targeting multidrug-resistant bacterial infections.

Application

• Pharmaceutical API: Core active ingredient in the manufacture of antibiotic drugs, particularly for urinary tract infections (UTIs).
• Injectable Formulations: Used in the development of sterile parenteral solutions due to its good solubility profile.
• Oral Solid Dosage Forms: A key component in tablets and capsules designed for systemic antibiotic therapy.
• Veterinary Medicine: Employed in antibiotic preparations for treating bacterial infections in livestock and companion animals.
• Research & Development: Serves as a critical reference standard and intermediate in antimicrobial research and new drug discovery.
• Combination Therapies: Used in fixed-dose combination drugs to combat antibiotic resistance and broaden the spectrum of efficacy.

Basic Information

Product Name	Arginine Fosfomycin
CAS No.	70518-66-0
Molecular Formula	C9H21N4O5P
Molecular Weight	296.26 g/mol
Synonyms	Fosfomycin Arginine; Fosfomycin Arginine Salt; (2R,3S)-(3-Methyloxiran-2-yl)phosphonic Acid Arginine Salt; Arginine (2R,3S)-Epoxypropylphosphonate; Monurol Salt (Arginine); Antibiotic MK-955 Arginine Salt; Fosfomycin Trometamol Analog; L-Arginine Fosfomycin
EINECS	Contact for details

Quality Control

Our Arginine Fosfomycin is manufactured under strict quality management systems, targeting purity levels suitable for pharmaceutical applications. Each batch is tested to ensure identity, potency, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) is provided, detailing results for assay, related substances, residual solvents, and microbiological quality, in alignment with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity to prevent degradation and clumping.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm
Microbial Limits	Complies with Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.