Description

5-(Aminomethyl)-2'-Deoxyuridine is a modified nucleoside analog that serves as a critical building block in nucleic acid chemistry and biochemical research. This compound matters for its role as a versatile intermediate in the synthesis of oligonucleotides and probes, enabling advanced studies in molecular biology and drug discovery. It is primarily needed by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on developing novel diagnostics and therapeutic agents.

Application

• Oligonucleotide Synthesis: A key monomer for incorporating modified bases into synthetic DNA strands for research and diagnostic applications.
• Bioconjugation & Probe Development: The aminomethyl group provides a reactive handle for attaching fluorescent dyes, affinity tags, or other reporter molecules to create specialized probes.
• Antiviral & Anticancer Research: Used as a precursor in the development and study of nucleoside-based prodrugs and therapeutic agents.
• Biochemical Tool Development: Employed in creating substrates for enzyme studies, particularly those involving DNA repair mechanisms or nucleoside metabolism.
• Cross-linking Studies: Utilized in research to investigate DNA-protein interactions and nucleic acid structure.

Basic Information

Product Name	5-(Aminomethyl)-2'-Deoxyuridine
CAS No.	70465-55-3
Molecular Formula	C10H15N3O5
Molecular Weight	257.24 g/mol
Synonyms	5-(Aminomethyl)deoxyuridine; 5-(Aminomethyl)-2'-deoxyuridine; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(aminomethyl)pyrimidine-2,4-dione; 5-(Aminomethyl)dU; 5-AMDURD; 2'-Deoxy-5-(aminomethyl)uridine; 5-Carbamoylmethyl-2'-deoxyuridine (related structure)
EINECS	Contact for details

Quality Control

Our 5-(Aminomethyl)-2'-Deoxyuridine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a desiccated environment to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.